Supplementary Material Supplementary Tables 1 - 3: Click here to view. Control of mosquito-borne infectious diseases: sex and gene drive. Release rates required to control a population with a Y-linked editor as a function of the y-chromosome sex linked traits in Waterbury level of suppression and the intrinsic rate of increase of the population R m.
This is the case for all birds.
Late-acting dominant lethal genetic systems and mosquito control. It makes little difference in these cases whether the target gene is X-linked or autosomal. Release rates required to control a population with a Y-linked editor as a function of the desired level of suppression and the intrinsic rate of increase of the population R m.
Most of the Y chromosome genes are involved with essential cell house-keeping activities 16 genes and sperm production 9 gene families. In humans, there are 23 pairs or 46 chromosomes. It also y-chromosome sex linked traits in Waterbury in females who carry both mutant X chromosomes homozygous for the gene mutation.
The reason for this is that, in each somatic cell of a normal female, one of the X chromosomes is randomly deactivated. Article Media. The female is diploid and contains two sets of chromosomes, while the male is haploid. In X-linked recessive traits, the phenotype is expressed in males because they only have one X chromosome.
Male gametes contain only the Z chromosome.
We then examine the impacts of various deviations from the ideal, to assess the robustness of the approach, and the impacts of gene flow both into and out of the target population. Figure 2. We now consider two populations, one targeted for control and the other not, with some migration between them.
The problem gene that would cause the disorder is suppressed by the normal gene.